ELECTROPHYSIOLOGICAL COMPARISON OF NaV1.5 EXPRESSED IN HEK293 CELLS TO NATIVE NaV CURRENTS IN CARDIAC MYOCYTES

Contraction of cardiac muscle is a highly regulated event that relies on a delicate balance of ions entering and leaving the cell through ion channels. In particular, voltage gated sodium channels are responsible for the rapid depolarization that leads to a contraction. During an oxidative challenge...

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Bibliographic Details
Main Author: VALINSKY, WILLIAM COREY
Other Authors: Queen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.))
Language:en
en
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/1974/6658