MAPPING AND ANTAGONIZING THE INTERACTION BETWEEN PHOSPHODIESTERASE 3B AND EXCHANGE PROTEIN ACTIVATED BY cAMP-1 ELUCIDATES THEIR ROLES IN ENDOTHELIAL CELL ADHESION

The ubiquitous second messenger cAMP acts to integrate and translate information encoded by extracellular messenger molecules, including hormones and neurotransmitters. Intracellular cAMP concentrations are regulated through coordinated changes in the activities of adenylyl cyclases (ACs) and cyclic...

Full description

Bibliographic Details
Main Author: PRITCHARD, LISA
Other Authors: Queen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.))
Format: Others
Language:en
en
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1974/5269