The role of Mcl-1 in the response of human colorectal cancer cells to treatment with dichloroacetate
Dichloroacetate (DCA) it a metabolic reprogramming agent that is used to target the unique metabolism of cancer cells, but is not always effective in colorectal cancer cells. In HCT116 cells, DCA was unable to induce apoptosis, but did decrease proliferation when compared to untreated cells. A decre...
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| Language: | en |
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2013
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| Online Access: | http://hdl.handle.net/10214/7418 |