Development of a method to generate a soluble substrate for lytic transglycosylases
Peptidoglycan, the major component of the bacterial cell wall, is essential for cell viability. Several important antibiotics disrupt peptidoglycan metabolism, including the β-lactams and vancomycin. There are several bacterial enzymes involved in peptidoglycan metabolism that are not yet the target...
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| Language: | en |
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2011
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| Online Access: | http://hdl.handle.net/10214/2644 |