The role of NK1.1S+ cells and TH1 cytokines in the pathogenesis of acute murine graft-versus-host disease (GVHD)

Previous studies using a murine F1-hybrid model of acute GVHD have shown that mortality is prevented if the graft is depleted of NK1.1 + cells. The precise role played by these cells in the pathogenesis of GVHD has not been elucidated, but it is thought that they injure host target tissues. Two cyt...

Full description

Bibliographic Details
Main Author: Ellison, Cynthia A.
Format: Others
Language:en
en_US
Published: 2007
Online Access:http://hdl.handle.net/1993/1780