A novel method to increase depth of imaging in optical coherence tomography using ultrasound

Optical coherence tomography (OCT) is a biomedical imaging technique with many current applications. A limitation of the technique is its shallow depth of imaging. A major factor limiting imaging depth in OCT is multiple-scattering of light. This thesis proposes an integrated computational imgagi...

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Bibliographic Details
Main Author: Pereira Bogado, Pedro Fernando
Other Authors: Sherif, Sherif (Electrical and Computer Engineering)
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1993/8864
Description
Summary:Optical coherence tomography (OCT) is a biomedical imaging technique with many current applications. A limitation of the technique is its shallow depth of imaging. A major factor limiting imaging depth in OCT is multiple-scattering of light. This thesis proposes an integrated computational imgaging approach to improve depth of imaging in OCT. In this approach ultrasound patterns are used to modulate the refractive index of tissue. Simulations of the impact of ultrasound on the refractive index are performed, and the results are shown in this thesis. Simulations of the impact of the modulated refractive index on the propagation of light in tissue are needed. But there is no suitable simulator available. Thus, we implemented a Monte Carlo method to solve integral equations that could be used to perform these simulations. Results for integral equations in 1-D and 2-D are shown.