The use of glutamate and dipeptides as substitutes for glutamine in animal cell cultures

The chemical decomposition and cellular metabolism of glutamine in animal cell cultures results in ammonium accumulation in the growth medium. Less ammoniagenic substrates including glutamate and dipeptides (ala-gln and gly-gln) were investigated as substitutes for glutamine in cell culture. The CC...

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Bibliographic Details
Main Author: Christie, Andrew D.
Language:en_US
Published: 2007
Online Access:http://hdl.handle.net/1993/734