Effects of PARP-1 signaling and conjugated linoleic acid on brain cell bioenergetics and survival

Effects of PARP-1 signaling and conjugated linoleic acid on brain cell bioenergetics and survival

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Glutamate is the primary excitatory neurotransmitter in the central nervous system. Extracellular glutamate concentrations are tightly regulated to avoid over-stimulation of glutamate receptors, which leads to a cascade of deleterious processes collectively known as excitotoxicity. Excitotoxicity is...

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Bibliographic Details
Main Author: Hunt, Waylon T.
Other Authors: Anderson, Christopher (Pharmacology and Therapeutics)
Published: John Wiley and Sons 2012
Subjects:
CLA
Neurons
bioenergetics
PARP-1
Astrocytes
Stroke
Alzheimer's
excitotoxicity
Online Access:http://hdl.handle.net/1993/5070

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