Type 1 diabetes and bone mass, interrelationships with nutrient intake and physical activity in children and with dietary fish oil in weanling rats

An investigation was conducted in 8 to 18 year old children to determine interrelationships among Type 1 diabetes (DM 1), bone mass, nutrient intake and physical activity. Bone mineral content (BMC, g), bone area (BA, cm 2), and bone mineral density (BMD, g/cm2) were measured by dual-energy x-ray a...

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Main Author: Green, Kathy H.
Language:en_US
Published: 2007
Online Access:http://hdl.handle.net/1993/1989
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spelling ndltd-LACETR-oai-collectionscanada.gc.ca-MWU.1993-19892014-03-29T03:41:44Z Type 1 diabetes and bone mass, interrelationships with nutrient intake and physical activity in children and with dietary fish oil in weanling rats Green, Kathy H. An investigation was conducted in 8 to 18 year old children to determine interrelationships among Type 1 diabetes (DM 1), bone mass, nutrient intake and physical activity. Bone mineral content (BMC, g), bone area (BA, cm 2), and bone mineral density (BMD, g/cm2) were measured by dual-energy x-ray absorptiometry in children with (n = 27 females, 24 males) and without (n = 34 females, 34 males) DM 1. Nutrient intake was assessed using 3-day food records and physical activity by a validated questionnaire. Data was analyzed by two-way ANOVA and correlation analysis. Based on the results a second investigation was undertaken to study further the role of insulin in bone development, and the effect of n-3 PUFA on bone development in insulin deficiency. Weanling male Sprague-Dawley rats (n = 80) were randomly assigned to one of six groups: saline injection + pair-weigh (n = 20) or ad lib feeding (n = 20), or streptozotocin injection to induce insulin deficiency + ad lib feeding (n = 40). Animals were fed diet containing either soy oil or fish oil (menhaden + corn oil). (Abstract shortened by UMI.) 2007-05-22T15:12:08Z 2007-05-22T15:12:08Z 2001-03-01T00:00:00Z http://hdl.handle.net/1993/1989 en_US
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language en_US
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description An investigation was conducted in 8 to 18 year old children to determine interrelationships among Type 1 diabetes (DM 1), bone mass, nutrient intake and physical activity. Bone mineral content (BMC, g), bone area (BA, cm 2), and bone mineral density (BMD, g/cm2) were measured by dual-energy x-ray absorptiometry in children with (n = 27 females, 24 males) and without (n = 34 females, 34 males) DM 1. Nutrient intake was assessed using 3-day food records and physical activity by a validated questionnaire. Data was analyzed by two-way ANOVA and correlation analysis. Based on the results a second investigation was undertaken to study further the role of insulin in bone development, and the effect of n-3 PUFA on bone development in insulin deficiency. Weanling male Sprague-Dawley rats (n = 80) were randomly assigned to one of six groups: saline injection + pair-weigh (n = 20) or ad lib feeding (n = 20), or streptozotocin injection to induce insulin deficiency + ad lib feeding (n = 40). Animals were fed diet containing either soy oil or fish oil (menhaden + corn oil). (Abstract shortened by UMI.)
author Green, Kathy H.
spellingShingle Green, Kathy H.
Type 1 diabetes and bone mass, interrelationships with nutrient intake and physical activity in children and with dietary fish oil in weanling rats
author_facet Green, Kathy H.
author_sort Green, Kathy H.
title Type 1 diabetes and bone mass, interrelationships with nutrient intake and physical activity in children and with dietary fish oil in weanling rats
title_short Type 1 diabetes and bone mass, interrelationships with nutrient intake and physical activity in children and with dietary fish oil in weanling rats
title_full Type 1 diabetes and bone mass, interrelationships with nutrient intake and physical activity in children and with dietary fish oil in weanling rats
title_fullStr Type 1 diabetes and bone mass, interrelationships with nutrient intake and physical activity in children and with dietary fish oil in weanling rats
title_full_unstemmed Type 1 diabetes and bone mass, interrelationships with nutrient intake and physical activity in children and with dietary fish oil in weanling rats
title_sort type 1 diabetes and bone mass, interrelationships with nutrient intake and physical activity in children and with dietary fish oil in weanling rats
publishDate 2007
url http://hdl.handle.net/1993/1989
work_keys_str_mv AT greenkathyh type1diabetesandbonemassinterrelationshipswithnutrientintakeandphysicalactivityinchildrenandwithdietaryfishoilinweanlingrats
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