The association of the C677T 5,10methylenetetrahydrofolate reductase variant with elevated maternal serum α-fetoprotein and complications of pregnancy
Statement of problem: We have shown that the C677T 5,10 methylenetetrahydrofolate reductase (MTHFR) variant is associated with elevated maternal serum α-fetoprotein (MSAFP), the most common screening test for neural tube defects (NTD). Therefore, past contradictory studies of NTDs and C677T MTHFR ma...
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| Language: | en_US |
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2006
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| Online Access: | Björklund NK, Chodirker BN, Greenberg CR, Seargeant LE, Evans JA, C677T MTHFR frequencies in different Canadian Provinces. Electronic Letters: http://jmg.bmjjournals.com/cgi/eletters/40/8/619#46, J Med Genet, Nov. 23, 2003 http://hdl.handle.net/1993/101 |