A role for phosphatidylinositol 3-kinase in platelet aggregation

A role for phosphatidylinositol 3-kinase in platelet aggregation

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The aggregation of human platelets is an important physiological hemostatic event contingent upon receptor-dependent activation of the surface integrin GPIIb-IIIa and subsequent binding of fibrinogen. Previous studies have demonstrated that phosphatidylinositol 3-kinase (PI 3-kinase) is activated...

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Bibliographic Details
Main Author:	Stevens, Christiaan Simeon Michael
Language:	English
Published:	2009
Online Access:	http://hdl.handle.net/2429/9341

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