Statin-induced muscle mitochondrial toxicity
Statins are the mainstay of cholesterol-lowering therapy and are taken by millions of people worldwide. These drugs are generally well-tolerated but can cause myopathy ranging from mild muscle pain to fatal rhabdomyolysis. The mechanism of statin-induced myopathy (SIM) is not fully understood and th...
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| Language: | English |
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University of British Columbia
2008
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| Online Access: | http://hdl.handle.net/2429/908 |