Higher order chromatin structure of the tyrosinase gene locus

An important enhancer/MAR (matrix attachment region) regulatory element in the mouse tyrosinase locus, located 15 kb upstream of the transcription initiation site, is responsible for imparting high level, position-independent tyrosinase transgene expression in neural crest-derived melanocytes. As...

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Bibliographic Details
Main Author: Rempel, Allan
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/9028