Unsaturated analogues of valproic acid : structure activity relationships and interaction with gaba metabolism
Vaiproic acid (VPA) is a versatile clinical antiepileptic drug which is also characterized by rare but potentially fatal side effects such as hepatotoxicity and teratogenicity. Its principal metabolite, the α,β-unsaturated acid 2-ene VPA, appears to share most of VPA’s therapeutic properties whil...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/8954 |
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