Antibody-catalyzed formation of a 14-membered ring lactone
A number of macrolide antibiotics have a 14-membered ring lactone skeleton. Besides the stereochemical challenges associated with the syntheses of these macrocyclic compounds, the difficulty in controlling the ring forming step has provided the basis for many synthetic organic methodology studies...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/7424 |