Development of a modular synthesis of unsymmetrically substituted heterocycles with functional group tolerant N,O-chelated group 4 hydroamination precatalysts
The development of a synthetic approach to 2,5-unsymmetrically substituted piperazines from readily available terminal alkynes and amine substrates employing both intermolecular and intramolecular hydroamination methodologies developed in the Schafer group is reported in this thesis. The approach re...
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| Language: | English |
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University of British Columbia
2014
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| Online Access: | http://hdl.handle.net/2429/46847 |