Contribution of p-glycoprotein mediated-efflux to the epithelial transport of amphotericin b in caco-2 cells

Contribution of p-glycoprotein mediated-efflux to the epithelial transport of amphotericin b in caco-2 cells

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Background: Amphotericin B (AmB) is a highly efficacious therapeutic for invasive fungal infections (IFIs) and protozoal diseases. Increasing prevalence of these conditions necessitates the development of an oral AmB formulation, with reduced toxicity, improved tissue distribution, and improved aff...

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Bibliographic Details
Main Author:	Osei-Twum, Jo-Ann B.
Language:	English
Published:	University of British Columbia 2014
Online Access:	http://hdl.handle.net/2429/46529

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