Antibiotic screening of plants used to treat infectious diseases in Kenya

This thesis presents a documentation of plants used in traditional medicine for infectious diseases in Kenya, followed by an analysis of antimicrobial activities of their methanolic extracts. In the first part of this study discussions were held with herbalists from around the Arabuko Sokoke fore...

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Main Author: Mutta, Doris N.
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/4524
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spelling ndltd-LACETR-oai-collectionscanada.gc.ca-BVAU.2429-45242014-03-14T15:39:46Z Antibiotic screening of plants used to treat infectious diseases in Kenya Mutta, Doris N. This thesis presents a documentation of plants used in traditional medicine for infectious diseases in Kenya, followed by an analysis of antimicrobial activities of their methanolic extracts. In the first part of this study discussions were held with herbalists from around the Arabuko Sokoke forest in Kilifi District and various other parts in Kenya. A total of 56 species belonging to 32 families were documented to treat infections of the gastrointestinal tract, skin and sexually transmitted diseases. This documentation effort will contribute towards preservation of the fragile indigenous knowledge currently threatened by influences of modernization. In the second part, a total of 60 extracts from 54 species were tested against selected pathogenic bacteria i.e. the acid fast bacterium - Mycobacterium phlei, four strains of gram positive bacteria -Bacillus subtilis, Staphylococcus aureus K147, S. aureus MR P0017 and Streptococcus faecalis, four strains of gram negative bacteria - Escherichia coli, Pseudomonas aeruginosa H187, P. aeruginosa H188, Salmonella typhimurium and two strains of yeast fungi Candida albicans and Saccharomyces cerevisiae. A total of 43 extracts of 39 nine species were active against at least one microorganism most of them having a strong link between the disease they are used to treat traditionally and the impact on the responsible bacteria and fungi. This linkage provides evidence for the presence of antibiotic substances and establishes, to some extent, the efficacy of the herbal remedies used for infectious diseases. 2009-02-12T17:27:52Z 2009-02-12T17:27:52Z 1995 2009-02-12T17:27:52Z 1996-11 Electronic Thesis or Dissertation http://hdl.handle.net/2429/4524 eng UBC Retrospective Theses Digitization Project [http://www.library.ubc.ca/archives/retro_theses/]
collection NDLTD
language English
sources NDLTD
description This thesis presents a documentation of plants used in traditional medicine for infectious diseases in Kenya, followed by an analysis of antimicrobial activities of their methanolic extracts. In the first part of this study discussions were held with herbalists from around the Arabuko Sokoke forest in Kilifi District and various other parts in Kenya. A total of 56 species belonging to 32 families were documented to treat infections of the gastrointestinal tract, skin and sexually transmitted diseases. This documentation effort will contribute towards preservation of the fragile indigenous knowledge currently threatened by influences of modernization. In the second part, a total of 60 extracts from 54 species were tested against selected pathogenic bacteria i.e. the acid fast bacterium - Mycobacterium phlei, four strains of gram positive bacteria -Bacillus subtilis, Staphylococcus aureus K147, S. aureus MR P0017 and Streptococcus faecalis, four strains of gram negative bacteria - Escherichia coli, Pseudomonas aeruginosa H187, P. aeruginosa H188, Salmonella typhimurium and two strains of yeast fungi Candida albicans and Saccharomyces cerevisiae. A total of 43 extracts of 39 nine species were active against at least one microorganism most of them having a strong link between the disease they are used to treat traditionally and the impact on the responsible bacteria and fungi. This linkage provides evidence for the presence of antibiotic substances and establishes, to some extent, the efficacy of the herbal remedies used for infectious diseases.
author Mutta, Doris N.
spellingShingle Mutta, Doris N.
Antibiotic screening of plants used to treat infectious diseases in Kenya
author_facet Mutta, Doris N.
author_sort Mutta, Doris N.
title Antibiotic screening of plants used to treat infectious diseases in Kenya
title_short Antibiotic screening of plants used to treat infectious diseases in Kenya
title_full Antibiotic screening of plants used to treat infectious diseases in Kenya
title_fullStr Antibiotic screening of plants used to treat infectious diseases in Kenya
title_full_unstemmed Antibiotic screening of plants used to treat infectious diseases in Kenya
title_sort antibiotic screening of plants used to treat infectious diseases in kenya
publishDate 2009
url http://hdl.handle.net/2429/4524
work_keys_str_mv AT muttadorisn antibioticscreeningofplantsusedtotreatinfectiousdiseasesinkenya
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