Identifying functional single nucleotide polymorphisms in two candidate genes (PROC and PCSK9) in sepsis

Genetic variation contributes to outcome from sepsis. A large number of associations have been observed between genetic variants and sepsis outcome, however, identification of causal single nucleotide polymorphisms (SNPs), or their mechanisms of action, have not been successfully elucidated. The a...

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Bibliographic Details
Main Author: Thain, Katherine Roberta
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/44755

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