Overexpression of TDP-43 inhibits NF-κB activity by blocking p65 nuclear translocation
TDP-43 (TAR DNA binding protein 43) is a heterogeneous nuclear ribonucleoprotein (hnRNP) that has been found to be mainly responsible for neurodegenerative diseases recently. Its involvement in nuclear factor-kappaB pathways has been reported in neuron and microglial cells that are linked to amyo...
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| Language: | English |
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University of British Columbia
2013
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| Online Access: | http://hdl.handle.net/2429/44260 |