Role of PTP-alpha in integrated c-Kit and Fc-epsilon R1 mast cell activation
Mast cells (MCs) play a crucial role in the induction of allergic asthma by secreting inflammatory mediators in response to allergens. In addition to MC activation via the antigen/IgE receptor FcεR1, MC tissue recruitment and responsiveness is greatly enhanced by co-stimulation with the stem cell fa...
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| Language: | English |
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University of British Columbia
2012
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| Online Access: | http://hdl.handle.net/2429/40340 |