Effects of acute moderate hypoxemia on the pharmacokinetics of metoclopramide and its metabolites in chronically instrumented sheep
Hypoxemia is known to induce various physiological changes which can result in pharmacokinetic changes. To examine the effect of acute, moderate hypoxemia in metoclopramide (MCP) pharmacokinetics, a continuous infusion [14 hours] of MCP was administered during pre-hypoxemia (2hr), hypoxemia (6hr)...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/3531 |