Bioprocess development for the cell-based treatment of diabetes

The widespread cellular treatment of type 1 diabetes by islet transplantation is limited by tissue shortage and graft rejection. This work describes two novel bioprocesses to immobilize pancreatic cells in alginate using: (1) hollow fiber bioreactors or (2) alginate bead generation by an adapted...

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Bibliographic Details
Main Author: Hoesli, Corinne
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/30255