Cadherin-linked molecular mechanisms governing the terminal differentiation of human trophoblastic cells in vitro
Background: The formation of the multinucleated syncytial trophoblast of the human placenta is a critical step in pregnancy, which is prone to failure. In these studies, I have examined the role of TWIST, a transcription factor identified as a key repressor of E-cad expression in normal and cancer...
Main Author: | |
---|---|
Language: | English |
Published: |
University of British Columbia
2010
|
Online Access: | http://hdl.handle.net/2429/27098 |