Cadherin-linked molecular mechanisms governing the terminal differentiation of human trophoblastic cells in vitro

Background: The formation of the multinucleated syncytial trophoblast of the human placenta is a critical step in pregnancy, which is prone to failure. In these studies, I have examined the role of TWIST, a transcription factor identified as a key repressor of E-cad expression in normal and cancer...

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Bibliographic Details
Main Author: Ng, York Hunt
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/27098