The Effect of acetaminophen on isoniazid metabolism

Acetaminophen (APAP, paracetamol, N-acetyl-p-aminophenol), an analgesic and antipyretic drug, causes liver necrosis in overdose. Isoniazid (INH, isonicotinyl hydrazide), an antituberculous drug, also causes liver damage in some patients at therapeutic doses. The two medications are likely to be take...

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Bibliographic Details
Main Author: Youssefi, Mohammed
Language:English
Published: 2008
Online Access:http://hdl.handle.net/2429/2350