Functional characterization of human variants of NFKBIA : a key regulator of immune responsiveness implicated in susceptibility to infectious and inflammatory disease
IkBα is an important regulator of inflammation. Single nucleotide polymorphisms (SNPs) rs3138053, rs2233406 and rs2233409 in the promoter of the gene NFKBIA, which encodes for IkBα, have been shown to be associated with a variety of infectious and inflammatory conditions. In this study, we investiga...
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| Language: | English |
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University of British Columbia
2010
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| Online Access: | http://hdl.handle.net/2429/22659 |