CNS pharmacokinetics of diphenhydramine in sheep

The CNS pharmacokinetics of the Hrreceptor antagonist, diphenhydramine (DPHM), was studied in 100 d (103.5 ± 1.7 d) and 120 d (124.1 ± 1.4 d) fetuses, 10 cl (11.5 ± 1.6 d) and 30 d (33.8 ± 1.2 d) newborn lambs, and adult sheep (5.21 ± 2.83 years) using in vivo microdialysis. The first study invo...

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Bibliographic Details
Main Author: Yeung, Sam Au
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/15107