Xist and its role in X-chromosome inactivation

Xist and its role in X-chromosome inactivation

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Compensation for the two-fold dosage difference in female versus male mammals for X-linked genes involves the formation of an extremely stable heterochromatin structure on one of the two X chromosomes in females. Expression of the untranslated RNA, XIST, is required in cis for the establishment o...

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Bibliographic Details
Main Author:	Chow, Jennifer Christa
Language:	English
Published:	2009
Online Access:	http://hdl.handle.net/2429/14952

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