Xist and its role in X-chromosome inactivation
Compensation for the two-fold dosage difference in female versus male mammals for X-linked genes involves the formation of an extremely stable heterochromatin structure on one of the two X chromosomes in females. Expression of the untranslated RNA, XIST, is required in cis for the establishment o...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/14952 |