Studies of XIST and macroH2A1.2 independent of gene silencing : subtitle a unique hybrid cell model system

X chromosome inactivation results in the transcriptional silencing of one of the two X chromosomes present in mammalian female cells. XIST expression from the inactive X (Xi), and subsequent coating of the Xi by the XIST RNA, marks the initial major observable characteristic of X-inactivation. Th...

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Bibliographic Details
Main Author: Kwok, Edmund
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/12829