An investigation of the potential role of PKC isoforms in the regulation of acetyl-CoA carboxylase-1
Acetyl-CoA carboxylase (ACC) catalyzes the conversion of acetyl-CoA to malonyl-CoA, the first committed step in de novo fatty acid synthesis. Although the enzyme is activated in response to insulin, the mechanism of activation is unclear. In adipose tissue, ACC is phosphorylated on a distinct sit...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/11510 |