Role of immunoregulation in the development of dermal fibrosis in tight-skin mice
The tight-skin (Tsk/+) mutant mouse serves as an experimental model for human scleroderma, a connective tissue disorder characterized by excessive deposition of collagen and other extracellular matrix molecules predominantly within the dermal regions, leading to the development of fibrosis. The p...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/11176 |