The roles of the IG-alpha and IG-beta cytoplasmic domains in B cell antigen receptor (BCR) internalization and trafficking

The B cell antigen receptor (BCR) is expressed on the surface of B lymphocytes where it can bind antigen then transmit signals which regulate activation, growth, and differentiation. These signals can induce a number of cytoskeletal rearrangements leading to changes in adherence, spreading, polarity...

Full description

Bibliographic Details
Main Author: Jang, Caren Lynn
Format: Others
Language:English
Published: University of British Columbia 2009
Online Access:http://hdl.handle.net/2429/5747