Novel function of coagulation factor Xa : conversion into a clot-dissolving cofactor

PLASMIN-MEDIATED CONVERSION OF FXa INTO A CLOT-DISSOLVING COFACTOR. Factor Xa (FXa) is an essential blood clotting enzyme. A previously identified FXa derivative, Xa33/13, is generated by two distinct cleavages by the clot-dissolving (fibrinolytic) enzyme, plasmin. FXa is first converted to FXaβ by...

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Bibliographic Details
Main Author: Vanden Hoek, Amanda Lynne
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/36854

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