Characterization of the Dicistroviridae intergenic region internal ribosome entry site

The IRES found in the intergenic (IGR) region of viruses belonging to the Dicistroviridae family is remarkable for its ability to bind directly to the ribosome with high affinity and initiate translation without the requirement for any initiation factors by mimicking a P/E hybrid tRNA. Here, we have...

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Bibliographic Details
Main Author: Jang, Christopher
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/35330