Topical and local controlled release of stratifin for the improvement of hypertrophic scarring in open and surgically closed wounds
Hypertrophic scar (HS), which results from the uncontrolled synthesis and excessive deposition of extracellular matrix (ECM) at sites of dermal injury, represents an undesirable endpoint of wound healing. Stratifin (SFN) was recently identified as a potent matrix methaloproteinase-1 (MMP-1) stimulat...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/31667 |