XIST/Xist-induced epigenetic events in somatic cells
Mammalian dosage compensation of X-linked genes is achieved between XX females and XY males by silencing one of the two X chromosomes. It is the expression of a functional non-coding RNA transcript, XIST that is responsible for the initiation of silencing during X-chromosome inactivation. XIST expre...
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| Language: | English |
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University of British Columbia
2010
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| Online Access: | http://hdl.handle.net/2429/23811 |