Identification and characterization of CIS-acting regulatory elements for human x-inactive specific transcript

Dosage compensation in female mammals is achieved by XIST/Xist RNA mediated transcriptional silencing of one of the two X chromosomes. Several developmental specific cis-acting regulatory elements for mouse XIST have been demonstrated. One of these regulatory elements is the mouse Tsix locus, which...

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Bibliographic Details
Main Author: Chang, Chia-Yu
Format: Others
Language:English
Published: University of British Columbia 2009
Online Access:http://hdl.handle.net/2429/15880