Modeling mammary epithelial cell polarization and the role of podocalyxin in breast tumor progression
The mammary gland consists of an organized network of epithelial ducts and lobules. This histoarchitecture can be recapitulated in vitro by culturing mammary epithelial cells as 3D spheroids embedded in a reconstituted basement membrane. I first used this assay to characterize the role of cell-cell...
Main Author: | |
---|---|
Format: | Others |
Language: | English |
Published: |
University of British Columbia
2008
|
Subjects: | |
Online Access: | http://hdl.handle.net/2429/1523 |