Modeling mammary epithelial cell polarization and the role of podocalyxin in breast tumor progression

The mammary gland consists of an organized network of epithelial ducts and lobules. This histoarchitecture can be recapitulated in vitro by culturing mammary epithelial cells as 3D spheroids embedded in a reconstituted basement membrane. I first used this assay to characterize the role of cell-cell...

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Bibliographic Details
Main Author: Graves, Marcia Lynn
Format: Others
Language:English
Published: University of British Columbia 2008
Subjects:
Online Access:http://hdl.handle.net/2429/1523