Synthesis and evaluation of an [18F]-labelled antisense oligonucleotide as an imaging probe to measure cellular response to radiation therapy
Antisense oligodeoxynucleotides (asODNs) show strong binding and high selectivity and can be constructed to recognize specific cellular targets such as gene regulated mRNA. Radiolabelled asODNs have the potential to image gene expression through mRNA targeting and could be a valuable tool in the ear...
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| Format: | Others |
| Language: | en |
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2010
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| Online Access: | http://hdl.handle.net/10048/1267 |