Karboanhidrazių slopiklių sintezė ir jų struktūros - aktyvumo tyrimas

Karboanhidrazių slopiklių sintezė ir jų struktūros - aktyvumo tyrimas

Show other versions (1)

Šio darbo tikslas – potencialių žmogaus karboanhidrazių (CA) slopiklių sintezė ir jų struktūros – aktyvumo tyrimas. CA slopinimo tyrimams susintetinti 136 įvairiais heterociklais pakeisti benzensulfonamidai ir išmatuotas jų CA I, II, VI, XII ir XIII slopinimo aktyvumas (VU BTI mokslininkai). Paruošt...

Full description

Bibliographic Details
Main Author:	Čapkauskaitė, Edita
Other Authors:	BUTKUS, EUGENIJUS
Format:	Doctoral Thesis
Language:	Lithuanian
Published:	Lithuanian Academic Libraries Network (LABT) 2012
Subjects:	Chemistry Karboanhidrazė Benzensulfonamidas Terminio poslinkio analizė Atrankumas Junginių kompleksų su CA rentgenostruktūrinė analizė Carbonic anhydrase Benzenesulfonamide Thermal shift assay Selectivity X-ray cocrystal structure
Online Access:	http://vddb.laba.lt/fedora/get/LT-eLABa-0001:E.02~2012~D_20121211_095550-70885/DS.005.0.01.ETD

Similar Items

Synthesis of carbonic anhydrase inhibitors and analysis of their structure - activity relationship
by: Čapkauskaitė, Edita
Published: (2012)

Rekombinantinių žmogaus karboanhidrazių I, II, VII, IX, XIII sąveikos su ligandais tyrimas
by: Baranauskienė, Lina
Published: (2013)

Pirimidino junginių - potencialių karboanhidrazių slopuklių - sintezė ir savybės
by: Sūdžius, Jurgis
Published: (2011)

Analysis of ligand binding to recombinant human carbonic anhydrases I, II, VII, IX and XIII
by: Baranauskienė, Lina
Published: (2013)

Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation
by: Mohamed A. Abdelrahman, et al.
Published: (2020-01-01)

Designing, synthesis and bioactivities of 4-[3-(4-hydroxyphenyl)-5-aryl-4,5-dihydro-pyrazol-1-yl]benzenesulfonamides
by: Halise Inci Gul, et al.
Published: (2017-01-01)

Struktūros ir veikėjo santykis diskurso analizėje
by: Agnė Girkontaitė
Published: (2018-11-01)

Synthesis, Molecular Docking Analysis, and Carbonic Anhydrase Inhibitory Evaluations of Benzenesulfonamide Derivatives Containing Thiazolidinone
by: Zuo-Peng Zhang, et al.
Published: (2019-06-01)

Specific anal ulcer treatment in immunocompromised patients: A prospective study
by: M.A. Bocaletti-Girón, et al.
Published: (2016-04-01)

Dar dėl <em>an </em>tipo junginių siaurinimo
by: Zigmas Zinkevičius
Published: (2011-05-01)

Fístulas anales
by: Jorge Arturo Sánchez S., et al.
Published: (1981-07-01)

Postpartum anal incontinence
by: A. L. Petrushin, et al.
Published: (2019-05-01)

Synthetic Strategies and Computational Inhibition Activity Study for Triazinyl-Substituted Benzenesulfonamide Conjugates with Polar and Hydrophobic Amino Acids as Inhibitors of Carbonic Anhydrases
by: Mária Bodnár Mikulová, et al.
Published: (2020-05-01)

Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives
by: Rosaria Gitto, et al.
Published: (2019-01-01)

Clinical and manometric evaluation of women with chronic anal fissure before and after internal subcutaneous lateral sphincterotomy
by: Silvana Marques e Silva, et al.
Published: (2012-06-01)

Hidrotalcito hidroterminė sintezė, savybės ir panaudojimas
by: Bankauskaitė, Agnė
Published: (2014)

Evaluation of botulinum toxin therapy for chronic anal fissure
by: Amr Abu El-Ella, et al.
Published: (2018-01-01)

Pokalbio struktūros analizė kalbos įsisavinimo požiūriu
by: Balčiūnienė, Ingrida
Published: (2009)

Įmonių veiklos analizė – informacijos rinkimo, tyrimo ir vertinimo sistema
by: Jonas Mackevičius
Published: (2008-01-01)

Early anal gland adenocarcinoma with a characteristic submucosal tumor-like appearance: a case report
by: Mikito Mori, et al.
Published: (2018-07-01)

Produktų rinkinio formavimas, remiantis pelningumo analize
by: Saldys, Arnoldas
Published: (2014)

Įmonės duomenų statistinės analizės, panaudojant DBVS, galimybių tyrimas
by: Vasiliauskas, Žygimantas
Published: (2010)

A 12-year retrospective evaluation of anal pre-cancerous lesions and cancer in people living with HIV-1 infection in the Southeastern U.S
by: Yuanfan Ye, et al.
Published: (2021-02-01)

Exploring the attitudes of men who have sex with men on anal self-examination for early detection of primary anorectal syphilis: a qualitative study
by: Ei T. Aung, et al.
Published: (2021-09-01)

Prevalência e características das lesões anais mediadas pelo HPV em homens com HIV/AIDS
by: PEREIRA, Araíz Cajueiro Carneiro
Published: (2014)

Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors
by: Mohammad M. Al-Sanea, et al.
Published: (2019-01-01)

Adenocarcinoma of the anal canal: A report of two cases with review of literature
by: Medha Pradip Kulkarni, et al.
Published: (2016-01-01)

IMPORTANCE OF THE ANAL MANOMETRY IN THE JUDICIALMEDICAL EXPERTISE OF THE ANAL PENETRATION
by: Jelica Miljkovic, et al.
Published: (2001-11-01)

A 30 YEAR EXPERIENCE IN THE MANAGEMENT OF ANAL FISTULA.
by: Doureid Oueidat
Published: (2017-12-01)

Treatment of chronic anal fissure: Botulinum toxin (Dysport) versus lateral internal anal sphincterotomy
by: Asgari M, et al.
Published: (2010-12-01)

Anal tuberculosis presenting as refractory perianal abscess
by: Kotaro Sasahara, et al.
Published: (2021-09-01)

Esfinteroplastia anal en el tratamiento de la incontinencia fecal por trauma obstétrico
by: Javier Chinelli, et al.
Published: (2019-07-01)

Lesão intra-epitelial escamosa anal em mulheres atendidas no Serviço de Prevenção do Câncer Cervical do Hospital das Clínicas da UFPE
by: Castro do Rêgo Barros, Romualda
Published: (2014)

4-Amino-substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases
by: Kęstutis Rutkauskas, et al.
Published: (2014-10-01)

Open lateral internal anal sphincterotomy under local anesthesia as the gold standard in the treatment of chronic anal fissures: A prospective clinical and manometric study Esfinterotomía lateral interna abierta con anestesia local como gold standard en el tratamiento de la fisura anal crónica: Estudio prospectivo clínico y manométrico a largo plazo
by: A. Sánchez Romero, et al.
Published: (2004-12-01)

Analyzing the prevalence of proctological diseases in HIV-positive and -negative patients
by: Thiago da Silveira Manzione, et al.
Published: (2020-10-01)

Anal abscess microbiology as an anal fistula predictor
by: Victoria Eugenia Dowling Enez, et al.
Published: (2020-04-01)

A Novel Surgical Technique for Anal Fistula Surgery Designed to Preserve the Anal Sphincter Function and Anoderm
by: Yasuhiro Shimojima, et al.
Published: (2021-01-01)

A rare case of rectal cancer with perianal metastasis: a case report
by: Takuto Ikeda, et al.
Published: (2019-08-01)

mRNA Detection in Anal Cytology: A Feasible Approach for Anal Cancer Screening in Men Who Have Sex with Men Living With HIV
by: Marta Del Pino, et al.
Published: (2019-11-01)

Cannot write session to /tmp/vufind_sessions/sess_h1pkuuk87i96bul3ah4le87lj4