Human carboxylesterase 2 splice variants: expression, activity, and role in the metabolism of irinotecan and capecitabine
Indiana University-Purdue University Indianapolis (IUPUI) === Carboxylesterases (CES) are enzymes that metabolize a wide variety of compounds including esters, thioesters, carbamates, and amides. In humans there are three known carboxylesterase genes CES1, CES2, and CES3. Irinotecan (CPT-11) and c...
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| Language: | en_US |
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2009
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| Online Access: | http://hdl.handle.net/1805/1905 |