Avaliação da presença de mutações de resistência no gene da NS5B e do prognóstico da infecção pelo HCV através da IL-28B em pacientes monoinfectados com HCV no RJ

Avaliação da presença de mutações de resistência no gene da NS5B e do prognóstico da infecção pelo HCV através da IL-28B em pacientes monoinfectados com HCV no RJ

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Estima-se que a prevalência global da população mundial com hepatite C é de 3%. Pouco se sabe sobre a resposta ao tratamento com respeito à resistência viral. Algumas mutações no fragmento de 109 aminoácidos da NS5B são associadas com resistência ao interferon (IFN) e ribavirina (RBV). Estudos molec...

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Bibliographic Details
Main Author:	Magda Cristina Bernardino Castilho
Other Authors:	Orlando da Costa Ferreira Junior
Format:	Others
Language:	Portuguese
Published:	Universidade do Estado do Rio de Janeiro 2013
Subjects:	HCV NS5B Genotipagem Sequências brasileiras Mutações de resistência Citocinas Polimorfismos imunogenéticos Resposta virológica Genotyping Brazilian sequences Resistance mutation Mutation Cytokines Immunogenetics polymorphisms Virological Response IMUNOGENETICA
Online Access:	http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=6047

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