Mecanismos nociceptivos desencadeados pela ativação espinal dos receptores NOD2 (CARD15) na gênese da dor crônica

Mecanismos nociceptivos desencadeados pela ativação espinal dos receptores NOD2 (CARD15) na gênese da dor crônica

Entre os PRRs (receptores de reconhecimento padrão), NOD-like receptors (NLRs), tal como NOD2, são responsáveis pela detecção intracelular de muramil dipeptídeo (MDP); padrão molecular associado a patógeno (PAMP), encontrado no peptidoglicano (PGN) de praticamente todas bactérias GRAM positiva e...

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Bibliographic Details
Main Author:	David Wilson Ferreira
Other Authors:	Thiago Mattar Cunha
Language:	Portuguese
Published:	Universidade de São Paulo 2013
Subjects:	Astrócito Células da glia Dor crônica Hipersensibilidade Micróglia Muramil dipeptídeo NOD2 Receptor do tipo NOD Receptores de reconhecimento padrão Astrocytes Chronic pain Glial cells Hypersensitivity Microglia Muramyl dipeptide NOD-like receptors Pattern recognition receptors
Online Access:	http://www.teses.usp.br/teses/disponiveis/17/17133/tde-28052018-152655/

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