Desenvolvimento de anti-hTNFα terapêutico.

Desenvolvimento de anti-hTNFα terapêutico.

O objetivo do projeto foi desenvolver linhagens celulares para um anticorpo terapêutico anti-hTNFα e comprovar sua funcionalidade. Os genes anti-hTNFα foram clonados em células CHO para seleção da população estável mista, demonstrando expressão de anticorpo com reconhecimento d...

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Bibliographic Details
Main Author:	Mateus Dalcin Luchese
Other Authors:	Ana Maria Moro
Language:	Portuguese
Published:	Universidade de São Paulo 2016
Subjects:	Anticorpo terapêutico Autoimunidade Biossimilar/biossuperior Células CHO Geração de linhagem celular TNFα Autoimmunity Biosimilar/biobetter Cell line generation CHO cells Therapeutic antibody
Online Access:	http://www.teses.usp.br/teses/disponiveis/87/87131/tde-26082016-105426/

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