Atividade da proteína quinase dependente de RNA (PKR) no sistema nociceptivo em um modelo experimental de neuropatia periférica de origem viral

Atividade da proteína quinase dependente de RNA (PKR) no sistema nociceptivo em um modelo experimental de neuropatia periférica de origem viral

A proteína quinase dependente de RNA (PKR) é uma molécula sentinela ativada em situações de estresse celular, incluindo infecções virais. A ativação de PKR por meio de sua fosforilação aciona cascatas de sinalização intracelular envolvidas em respostas inflamatórias e inibição da síntese protéic...

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Bibliographic Details
Main Author:	Clarissa Maria Dias Mota
Other Authors:	Guilherme de Araujo Lucas
Language:	Portuguese
Published:	Universidade de São Paulo 2016
Subjects:	Dor crônica Neuralgia herpética Neuralgia pós-herpética Neuropatia periférica PKR Vírus herpes simples tipo 1 Chronic pain Herpes simplex virus type-1 Herpetic neuralgia Peripheral neuropathy Post-herpetic neuralgia
Online Access:	http://www.teses.usp.br/teses/disponiveis/17/17134/tde-21072016-143055/

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