$Diferenças Estruturais e \"Docking\" Receptor-Ligante da Proteína E7 do Vírus do Papiloma Humano (HPV) de Alto e Baixo Riscos para o Câncer Cervical.$

Diferenças Estruturais e \"Docking\" Receptor-Ligante da Proteína E7 do Vírus do Papiloma Humano (HPV) de Alto e Baixo Riscos para o Câncer Cervical.

O câncer cervical afeta milhões de mulheres em todo o mundo a cada ano. A maioria dos casos de câncer cervical é causada pelo vírus do papiloma humano (HPV) que é sexualmente transmissível. Cerca de 40 tipos de HPV infectam o colo do útero e estes são designados como sendo de alto ou de baixo ri...

Full description

Bibliographic Details
Main Author:	Nilson Nicolau Junior
Other Authors:	Silvana Giuliatti
Language:	Portuguese
Published:	Universidade de São Paulo 2013
Subjects:	Desordem intrínseca Dinâmica molecular Docking E7 Farmacóforos HPV Modelagem macromolecular Intrinsically disorder Macromolecular modeling Molecular dynamics Pharmacophores
Online Access:	http://www.teses.usp.br/teses/disponiveis/17/17135/tde-13062013-092311/

Similar Items

Diferenças Estruturais e \"Docking\" Receptor-Ligante da Proteína E7 do Vírus do Papiloma Humano (HPV) de Alto e Baixo Riscos para o Câncer Cervical.
by: Nicolau Junior, Nilson
Published: (2013)

Molecular Docking Explains Atomic Interaction between Plant-originated Ligands and Oncogenic E7 Protein of High Risk Human Papillomavirus Type 16
by: Satish Kumar, et al.
Published: (2014-12-01)

Accounting for Large Amplitude Protein Deformation during in Silico Macromolecular Docking
by: Chantal Prévost, et al.
Published: (2011-02-01)

Elucidating Molecular Interactions of Natural Inhibitors with HPV-16 E6 Oncoprotein through Docking Analysis
by: Satish Kumar, et al.
Published: (2014-06-01)

Improving Posing and Ranking of Molecular Docking
by: Wallach, Izhar
Published: (2012)

Improving Posing and Ranking of Molecular Docking
by: Wallach, Izhar
Published: (2012)

Modeling and Molecular Dynamics of the 3D Structure of the HPV16 E7 Protein and Its Variants
by: Ciresthel Bello-Rios, et al.
Published: (2021-01-01)

DARS-RNP and QUASI-RNP: New statistical potentials for protein-RNA docking
by: Bujnicki Janusz M, et al.
Published: (2011-08-01)

Identification of CDK7 Inhibitors from Natural Sources Using Pharmacoinformatics and Molecular Dynamics Simulations
by: Vikas Kumar, et al.
Published: (2021-09-01)

In Silico Studies of Quinoxaline-2-Carboxamide 1,4-di-N-Oxide Derivatives as Antimycobacterial Agents
by: Awwad A. Radwan, et al.
Published: (2014-02-01)

In silico identification and biochemical validation of plausible molecular targets of 4-thiazolidinone derivative Les-3833 as a potential anticancer agent
by: L. Kоbylinska, et al.
Published: (2021-04-01)

Evolution of Macromolecular Docking Techniques: The Case Study of Nickel and Iron Metabolism in Pathogenic Bacteria
by: Francesco Musiani, et al.
Published: (2015-08-01)

Cytotoxicity Of Chalcone Of Eugenia aquea Burm F. Leaves Against T47D Breast Cancer Cell Lines And Its Prediction As An Estrogen Receptor Antagonist Based On Pharmacophore-Molecular Dynamics Simulation
by: Muchtaridi M, et al.
Published: (2019-11-01)

Structure Based Design and Molecular Docking Studies for Phosphorylated Tau Inhibitors in Alzheimer’s Disease
by: Jangampalli Adi Pradeepkiran, et al.
Published: (2019-03-01)

Combined Pharmacophore Modeling, Docking, and 3D-QSAR Studies of PLK1 Inhibitors
by: Tao Lu, et al.
Published: (2011-12-01)

Discovery of Novel Focal Adhesion Kinase Inhibitors Using a Hybrid Protocol of Virtual Screening Approach Based on Multicomplex-Based Pharmacophore and Molecular Docking
by: Xiangrong Song, et al.
Published: (2012-11-01)

Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking and Biological Evaluation for Identification of Potential Poly (ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors
by: Yunjiang Zhou, et al.
Published: (2019-11-01)

Screening for cyclooxygenase 2 inhibitors from natural compounds of Radix Glycyrrhizae using computer simulation
by: Ming Yang, et al.
Published: (2018-05-01)

Combinatorial In Silico Strategy towards Identifying Potential Hotspots during Inhibition of Structurally Identical HDAC1 and HDAC2 Enzymes for Effective Chemotherapy against Neurological Disorders
by: Shabir Ahmad Ganai, et al.
Published: (2017-11-01)

Análise da madeira de Pinus oocarpa parte I: estudo dos constituintes macromoleculares e extrativos voláteis Chemical analysis of Pinus oocarpa wood part I: quantification of macromolecular components and volatile extractives
by: Sérgio Antônio Lemos de Morais, et al.
Published: (2005-06-01)

Development of novel HER2 inhibitors against gastric cancer derived from flavonoid source of Syzygium alternifolium through molecular dynamics and pharmacophore-based screening
by: Babu TMC, et al.
Published: (2016-11-01)

Computational Prediction of RNA-Binding Proteins and Binding Sites
by: Jingna Si, et al.
Published: (2015-11-01)

Contribution to the Understanding of Protein–Protein Interface and Ligand Binding Site Based on Hydrophobicity Distribution—Application to Ferredoxin I and II Cases
by: Mateusz Banach, et al.
Published: (2021-09-01)

Identification of New Potential APE1 Inhibitors by Pharmacophore Modeling and Molecular Docking
by: In Won Lee, et al.
Published: (2017-12-01)

Identification of Novel Src Inhibitors: Pharmacophore-Based Virtual Screening, Molecular Docking and Molecular Dynamics Simulations
by: Yi Zhang, et al.
Published: (2020-09-01)

Regulation of the Wnt/β-Catenin Signaling Pathway by Human Papillomavirus E6 and E7 Oncoproteins
by: Jesus Omar Muñoz Bello, et al.
Published: (2015-08-01)

Studies on the Nucleocytoplasmic Transport of the E7 Oncoprotein of High-Risk HPV Type 16
by: Eberhard, Jeremy
Published: (2013)

Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China
by: Jiaoyu He, et al.
Published: (2019-05-01)

Functional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical Sites
by: Vjekoslav Tomaić
Published: (2016-10-01)

Novel Hybrid Virtual Screening Protocol Based on Molecular Docking and Structure-Based Pharmacophore for Discovery of Methionyl-tRNA Synthetase Inhibitors as Antibacterial Agents
by: Cheng Peng, et al.
Published: (2013-07-01)

Structure-Based Pharmacophore Design and Virtual Screening for Novel Tubulin Inhibitors with Potential Anticancer Activity
by: Yunjiang Zhou, et al.
Published: (2019-09-01)

Virtual Screening for Potential Allosteric Inhibitors of Cyclin-Dependent Kinase 2 from Traditional Chinese Medicine
by: Fang Lu, et al.
Published: (2016-09-01)

Potential bioactive compounds as SARS-CoV-2 inhibitors from extracts of the marine red alga Halymenia durvillei (Rhodophyta) – A computational study
by: Asmi Citra Malina A.R. Tassakka, et al.
Published: (2021-11-01)

Drug Repurposing Approach against Novel Coronavirus Disease (COVID-19) through Virtual Screening Targeting SARS-CoV-2 Main Protease
by: Kamrul Hasan Chowdhury, et al.
Published: (2021-12-01)

Identification of Phosphatidylinositol 3-kinase δ (PI3Kδ) Inhibitor: Pharmacophore-based Virtual Screening and Molecular Dynamics Simulation
by: Muhammad Arba, et al.
Published: (2020-07-01)

Discovery of Novel Acetylcholinesterase Inhibitors as Potential Candidates for the Treatment of Alzheimer’s Disease
by: Minky Son, et al.
Published: (2019-02-01)

Dynamic Structure-Based Pharmacophore Model Development: A New and Effective Addition in the Histone Deacetylase 8 (HDAC8) Inhibitor Discovery
by: Keun Woo Lee, et al.
Published: (2011-12-01)

Busca virtual de compostos bioativos: conceitos e aplicações
by: Erika Piccirillo, et al.

Activity artifacts in drug discovery and different facets of compound promiscuity [v1; ref status: indexed, http://f1000r.es/4gz]
by: Jürgen Bajorath
Published: (2014-10-01)

HPV18 E7 induces the over-transcription of eIF4E gene in cervical cancer
by: Tianyun Pang, et al.
Published: (2015-07-01)

Cannot write session to /tmp/vufind_sessions/sess_bm1sjrdai2q10g4jvb4irij7ba