Investigação de mutações no gene PCSK9 em famílias com diagnóstico clínico de Hipercolesterolemia Familiar

Investigação de mutações no gene PCSK9 em famílias com diagnóstico clínico de Hipercolesterolemia Familiar

A hipercolesterolemia familiar (HF) é uma alteração de origem genética comum que pode se manifestar clinicamente desde o nascimento e provoca um aumento nos níveis plasmáticos de LDL-colesterol (LDL-c), xantomas e doença coronária prematura. Sua detecção e tratamento precoce reduzem a morbidade...

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Bibliographic Details
Main Author:	Aldrina Laura da Silva Costa Honorato
Other Authors:	Vivian Marques Miguel Suen
Language:	Portuguese
Published:	Universidade de São Paulo 2018
Subjects:	Doenças Cardiovasculares Hipercolesterolemia Familiar lipoproteína de baixa densidade proprotein convertase subtilisina kexin tipo 9 (PCSK9). Cardiovascular Diseases Familial Hypercholesterolemia low density lipoprotein, proprotein convertase subtilisin/kexin type 9 (PCSK9)
Online Access:	http://www.teses.usp.br/teses/disponiveis/17/17138/tde-07122018-091850/

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