Estudo de associação de fatores genéticos em indivíduos com reações de hipersensibilidade tardia induzida por anticonvulsivantes aromáticos

Estudo de associação de fatores genéticos em indivíduos com reações de hipersensibilidade tardia induzida por anticonvulsivantes aromáticos

Intrdodução: As terapias com anticonvulsivantes de anel aromático (ACA) são freqüentemente associadas a reações adversas. No entanto, reações de hipersensibilidade (RH) não-imediatas (tardias) a estes fármacos são raras, imprevisíveis e geralmente relacionadas à alta morbidade e mortalidade. Foi...

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Bibliographic Details
Main Author:	Luciana Kase Tanno
Other Authors:	Jorge Elias Kalil Filho
Language:	Portuguese
Published:	Universidade de São Paulo 2014
Subjects:	Anticonvulsivantes Antígenos de histocompatibilidade Farmacogenética Genética médica Hipersensibilidade a drogas Metabolismo Polimorfismo genético Síndrome de hipersensibilidade a medicamentos Síndrome de Stevens-Johnson Sistema enzimático do citocromo P-450 Anticonvulsants Cytochrome P450 Genetic polymorphism Histocompatibility antigens Hypersensitivity to drugs Hypersensitivity to drugs syndrome Medical genetics Pharmacogenetics, Metabolism Stevens-Johnson syndrome
Online Access:	http://www.teses.usp.br/teses/disponiveis/5/5146/tde-01122014-113756/

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