| Summary: | Made available in DSpace on 2014-08-20T14:31:33Z (GMT). No. of bitstreams: 1
dissertacao_luis_eduardo.pdf: 638136 bytes, checksum: bebab3fdb3ce4b3622bd9aa8729c10d2 (MD5)
Previous issue date: 2009-09-09 === Enteric parasitic infections are worldly known and reach mainly the poorest countries.
This problem becomes more serious when it is associated with the Human
Immunodeficiency Virus (HIV) infection. The objective of the study was to understand
the prevalence and the risk factors associated with the enteric parasites among AIDS
patients and HIV-positive healthy carriers. Cross-sectional study was carried out at
the single assistance health service specialized in HIV/AIDS on Pelotas, a city in
southern Brazil. Out of 273 patients who were interviewed in this study, 19,8% had
pathogenic enteric parasites, and the most frequent pathogens were Trichuris
trichiura, Giardia lamblia and Ascaris lumbricoides. The prevalence of pathogenic
enteric parasites was significantly higher (31,4%) among who were not undergoing
antiretroviral therapy (HAART) than among who were undergoing HAART (13,0%).
The frequency of opportunistic enteric parasites (Cryptosporidium spp.,
Cystoisospora belli and Strongyloides stercoralis) was low; and it was 1,9% and
2,4%, respectively, among who were and were not undergoing HAART. This
difference was not statistically significant. People with lower socioeconomic status,
who had domestic animals and were not undergoing antiretroviral therapy (HAART),
would have more chance to suffer from enteric parasitic infection when contrasted
with the compared groups. The study has shown that it is necessary to adopt and
carry out preventive and diagnosis actions among HIV-positive patients. === As parasitoses intestinais são conhecidas globalmente, atingindo especialmente
países mais pobres. Este problema se torna ainda mais grave quando associado à
infecção pelo vírus da imunodeficiência humana (HIV). O objetivo do estudo foi
estimar a prevalência e os fatores associados aos enteroparasitos em pacientes HIV
positivos. Foi realizado estudo transversal no único serviço de assistência
especializada em HIV/AIDS de Pelotas, RS. Do total de 273 entrevistados, 19,8%
estavam infectados por enteroparasitos patogênicos, sendo que os mais frequentes
foram Trichuris trichiura, Giardia lamblia e Ascaris lumbricoides. A prevalência de
parasitos patogênicos foi significativamente superior (31,4%) entre pacientes que
não estavam usando a terapia antirretroviral altamente potente e efetiva (HAART)
em relação aos que estavam usando HAART (13,0%). As prevalências foram baixas
para os parasitos intestinais oportunistas Cryptosporidium spp., Cystoisospora belli e
Strongyloides stercoralis, sendo de 2,4% em pacientes que não faziam uso de
HAART e de 1,9% em pacientes tratados com HAART, não havendo diferença
estatística. Os pacientes com níveis socioeconômicos mais baixos, que referiam ter
animais domésticos e que não faziam uso de terapia com HAART tiveram mais
chance de desenvolver enteroparasitos patogênicos. O estudo demonstra que é
necessária a adoção e implementação de medidas preventivas e de investigação
diagnóstica nos pacientes HIV positivos.
|
|---|
